Modern technology makes astrophotography with long exposure times easy. Guiding systems are used to keep the object exactly on the sensor. Either as a autoguider on a guide scope or using an off-axis guider in the primary light path. You can find both systems here.
The QHY5-III series camera is a USB3.0 super-speed camera with a Guide Port. It still uses the same standard 1.25-inch eyepiece adapter and has an adjustable location ring for confocality with an eyepiece. The QHY5-III comes in a very small but powerful package!